50 Innovative Life Sciences Companies to Watch in the Northeast

Life sciences companies include companies in the fields of biotechnology, pharmaceuticals, biomedical technologies, life systems technologies, cosmeceuticals, medical devices, and others that dedicate their efforts to research, development, and commercialization of products to improve people’s lives. Both patients and healthcare professionals benefit from the work of life sciences companies. While many people assume that these companies would locate in large metropolitan areas, there are more and more life sciences companies seeking the suburbs for lower overhead costs and to position themselves near educational institutions to aid in the research and development phases of their work.

One hotbed for life sciences companies is the northeast, and we have compiled a list of those that we think you should get to know. Our list includes only those life sciences companies that are emerging and among the most innovative today. We chose companies based on their promising pipelines, established products, innovative drug development programs, patented technologies, and level of expertise. These companies also employ approximately 200 people or more. Please note, we have listed these companies in no particular order.

1. Acorda Therapeutics

Acorda Therapeutics

Acorda Therapeutics is on a mission to develop therapies to improve the lives of those living with neurological disorders by developing therapies to restore function to patients suffering from nervous system disorders. The company has a rich product pipeline with nine products in various stages of research and development. Acorda’s partnerships and grant programs advance research and education as well, making them a life science company you should explore.

Notable Products:

Location: Ardsley, NY

2. Acusphere

Acusphere, Inc.

A specialty pharmaceutical company, Acusphere focuses on developing a cardiovascular drug for detecting coronary artery disease. The company realized there is a need for a fast, radiation-free, low cost procedure to detect coronary artery disease, and so they work toward developing Imagify to meet that need. Acusphere is a northeast life sciences company working to improve diagnostics and improve the patient experience.

Notable Product: Imagify

Location: Lexington, MA

3. AMAG Pharmaceuticals

AMAG Pharmaceuticals

AMAG Pharmaceuticals specializes in maternal health, anemia, and cancer supportive care. With a double-pronged goal, AMAG seeks to bring therapies with clear benefits and improvements to patients’ lives to market with its maternal health division, Lumara Health, and to make new advancements in patients’ health and make treatments more accessible. The company is working “to expand and diversify its portfolio through the in-license or purchase of additional pharmaceutical products or companies” and is an emerging life sciences company in the northeast.

Notable Products:

Location: Waltham, MA

4. Amneal Pharmaceuticals

Amneal Pharmaceuticals Inc.

Amneal Pharmaceuticals manufactures high-quality generic pharmaceuticals. A company involved throughout the entire product lifecycle, Amneal Pharmaceuticals, an emerging life science company in the northeast, is the seventh largest manufacturer, by prescription volume, of unbranded prescription products in the United States.

Notable Products:

Location: Bridgewater, NJ

5. Agenus


Agenus centers its work on the belief that “the best path for treating disease is through activating our own body’s natural mechanisms.” As a result, Agenus builds its technologies and products to treat cancers and infections “by helping the body’s immune system to target diseased cells with precision.” For example, Agenus has six preclinical programs focused on producing monoclonal antibodies that either block or activate specific checkpoint target receptors, making it an innovative northeast life science company.

Notable Products:

Location: Lexington, MA

6. Discovery Labs


Discovery Laboratories, Inc. has a niche in respiratory critical care. The company’s strategy originally focused on neonatology and improving respiratory distress syndrome (RDS) in premature infants. Now, Discovery Labs’ AEROSURF is its lead product development program to address RDS in premature infants, making it a northeast life sciences company you should know about.

Notable Products:

Location: Warrington, PA

7. Dyax


Recognized as a “Top Place to Work” by the Boston Globe in 2014, Dyax Corp. is a fully integrated biopharmaceutical company. Working to develop and commercialize treatments for hereditary angioedema (HAE), the company also dedicates its work to identifying other disorders that are mediated by plasma kallikrein (PKM disorders). Dyax is driven by the desire to improve patients’ lives and is quickly becoming an emerging life sciences company in the northeast.

Notable Products:

Location: Burlington, MA

8. Incyte

Incyte Pharmaceuticals

A biopharmaceutical company,  Incyte builds its pipeline of small molecule drugs primarily for oncology. Incyte strategically collaborates with top-tier pharmaceutical companies to deliver its therapeutics worldwide. With its broad pipeline of product candidates, Incyte is a northeast life sciences company you should get to know.

Notable Product: Jakafi

Location: Wilmington, DE

9. KVK-TECH, Inc.


KVK-TECH, a leading American developer, manufacturer, and marketer of specialty pharmaceuticals, makes all of its products in the USA and strictly adheres to FDA, DEA, and DEP guidelines. Currently KVK-Tech manufactures, markets, and distributes 11 drugs in the United States, making it an emerging life sciences company in the northeast.

Notable Products:

Location: Newtown, PA

10. Lannett Company, Inc.

Lannett Company, Inc.

A developer, manufacturer, and distributor of high-quality, affordable generic medications, Lannett Company has a product portfolio that dozens of products in a wide range of therapeutic areas. Lannett has three facilities in Philadelphia and is known as an industry leader that not only supports its customers but also supports its community by giving to schools, hospitals, veterans and their families, cancer research, local fire and police departments, and others.

Notable Products:

  • Acetazolamide
  • Clindamycin
  • Doxycycline
  • Rifampin

Location: Philadelphia, PA

11. Luitpold Pharmaceuticals, Inc.

Luitpold Pharmaceuticals

Luitpold Pharmaceuticals, Inc. develops and markets innovative, quality drugs and medical devices across the United States and Canada for healthcare professionals, clinics, and hospitals. Luitpold distributes its products through four divisions: American Regent, Regency Therapeutics, Animal Health, and Osteohealth. Additionally, Luitpold offers custom product development and contract manufacturing, helping it to earn a spot as an emerging life sciences company in the northeast.

Notable Products:

Location: Shirley, NY

12. Osiris Therapeutics, Inc.

Osiris Therapeutics, Inc.

Osiris Therapeutics is a leader in mesenchymal stem cell (MSC) science and the clinical application of cellular therapies. Osiris “has written the book on regenerative medicine,” and has established itself as the leading stem cell company. In an effort to continue to meet medical needs, Osiris takes an innovative approach when developing and marketing products in wound care, orthopedics, and sports medicine. Osiris has established itself as an emerging northeastern life sciences company.

Notable Products:

Location: Columbia, MD

13. Progenics Pharmaceuticals

Progenics Pharmaceuticals

Progenics Pharmaceuticals is becoming an emerging life sciences oncology company to be reckoned with, as it focuses on developing innovative drugs to improve the lives of prostate cancer patients and their families. With a pipeline that includes therapeutic and diagnostic candidates in all stages of development, Progenics looks to expand and complement their capabilities in the prostate cancer field.

Notable Products:

Location: Tarrytown, NY

14. SIGA Technologies

SIGA Technologies

SIGA Technologies, a pharmaceutical company, specializes in developing therapeutic solutions for smallpox, Ebola, dengue, Lassa fever, and other dangerous viruses. With a mission to discover and develop drugs as countermeasures to prevent and treat high-priority viral diseases that threaten global populations, SIGA Technologies has developed a discovery platform “that has shown promise with many pathogens.”

Notable Product: Tecovirimat


  • Corporate Headquarters: New York, NY
  • SIGA Labs: Corvallis, OR

15. Kadmon Pharmaceuticals

Kadmon Pharmaceuticals

As a pioneer in oncology, infectious diseases, immunology, and neurodegenerative diseases medicines, Kadmon Pharmaceuticals uses new molecular biology understandings to develop therapies targeting the metabolomic and signaling pathways associated with disease. Kadmon specializes in offering products and services for treating and managing hepatitis C. Innovating drug development with its own specialist-driven commercial platform and advancing a pipeline of novel small molecules and biologics, Kadmon is certainly an emerging life sciences company in the northeast.

Notable Products:


  • New York, NY
  • Warrendale, PA
  • Wilmington, MA
  • Monmouth Junction, NJ

16. Vanda Pharmaceuticals, Inc.

Vanda Pharmaceuticals, Inc.

Vanda Pharmaceuticals is a biopharmaceutical company dedicated to developing and commercializing products for treating central nervous system disorders. With an experienced team and a portfolio of clinical and commercial stage programs, Vanda strives to bring important new treatment options to patients. It already has achieved status as an emerging life science company in the northeast.

Notable Products:

Location: Washington, DC

17. Topix Pharmaceuticals, Inc.

Topix Pharmaceuticals, Inc.

Topix Pharmaceuticals, Inc. develops, manufactures, and markets innovative therapeutic and cosmetic skin care solutions. With an extensive product portfolio providing physicians with several product options, Topix helps them provide patient skin-type solutions and ‘condition-driven regimens.’ All Topix products are made in the U.S.A. from its Long Island-based facilities, which puts them in a perfect position as an emerging life sciences company in the northeast.

Notable Products:

Location: West Babylon, NY

18. Ironwood Pharmaceuticals

Ironwood Pharmaceuticals

With signifiant therapeutic expertise in gastrointestinal disorders and pharmacologic expertise in guanylate cyclase pathways, Ironwood Pharmaceuticals relies on its patients, shareholders, and employees to continue to shape their business, success, and future. They have discovery and development processes and a robust pipeline that has set them on the path to helping patients lead better lives and to emerging as a life sciences company in the northeast that is worth getting to know.

Notable product: Linzess

Location: Cambridge, MA

19. ARIAD Pharmaceuticals

ARIAD Pharmaceuticals

Dedicated to transforming the lives of cancer patients with their medicines, ARIAD Pharmaceuticals is an integrated oncology company. Currently, ARIAD’s focus is on advancing the treatment of various forms of chronic and acute leukemia, lung cancer, and other cancers that are difficult to treat. The company designs small molecule drugs to overcome resistance to existing cancer medicines, making it a life science company in the northeast that is worth knowing.

Notable Products:

Location: Cambridge, MA

20. Merrimack


Committed to fighting cancer, Merrimack strives to understand the disease’s complexity in order to “engineer life-saving solutions through our science.” Merrimack’s researchers work to apply systems biology as a tool to aid them in the discovery and development of better medicines. With six targeted therapeutic oncology candidates in  clinical development and multiple others in preclinical development, Merrimack has established itself as an emerging life sciences company in the northeast.

Notable Products:

  • MM-121
  • MM-111
  • MM-151
  • MM-141
  • MM-398
  • MM-302

Location: Cambridge, MA

21. Pacira Pharmaceuticals, Inc.

Pacira Pharmaceuticals, Inc.

With “a passion for delivering improved patient care,” Pacira Pharmaceuticals is committed to providing solutions in the post-surgical pain market. Their experience and knowledge of the market, as well as in the hospital marketplace, helps them to launch many acute care products and ensure that their products, pipeline, and partnerships are of consistently high quality. This also puts them in place as an emerging life science company in the northeast.

Notable Products:


  • Commercial and Business Development: Parsippany, NJ
  • Research & Development and Manufacturing Site: San Diego, CA
  • Torrey Pines Facility: La Jolla, CA

22. NPS Pharma

NPS Pharma

NPS Pharma dedicates itself to making a difference in the lives of patients living with rare diseases. That’s why the company is building a global pipeline of first-in-disease or best-in-disease therapies. Their goal is to develop a therapy for every person living with a rare disease, and their products and pipeline are making strides toward achieving that goal. All of this makes NPS Pharma an innovative life sciences company in the northeast.

Notable Products:

Location: Bedminster, NJ

23. Alnylam Pharmaceuticals

Alnylam Pharmaceuticals

A biopharmaceutical company that develops novel therapeutics based on RNA interferences (RNAi), Alnylam Pharmaceuticals’ core focus is on treating serious, life-threatening diseases that have only limited treatment options for patients. Using RNAi therapeutics, Alnylam seeks to develop and market innovative medicines with key characteristics to help them meet their goal.  Alnylam’s innovation makes them an emerging life sciences company in the northeast that you should know about.

Notable Products:

  • Patisiran (ALN-TTR02)
  • Revusiran for the treatment of FAC
  • ALN-AS1 for the treatment of hepatic porphyrias

Location: Cambridge, MA

24. Ikaria, Inc.

Ikaria, Inc.

Ikaria, a critical care company, focuses on developing and commercializing innovative therapies to address the needs of critically ill patients. Specifically, Ikaria seeks to provide advanced therapies and clinical support for caregivers so that they may intervene in urgent situations.

Notable Product: INOMAX

Location: Hampton, NJ

25. CorePharma


CorePharma develops, manufactures, and markets high-quality generic prescription pharmaceuticals spanning a variety of dosage forms and therapeutic categories. Currently producing more than 500 million tablets and capsules annually, CorePharma is known for its expertise in product development and manufacturing, robust sales, marketing, and distribution capabilities. Thus, CorePharma is an innovative northeastern life sciences company.

Notable Products:

  • Dextroamphetamine sulfate tablets (Dextrostat equivalent)
  • Oxymorphone hydrochloride tablets (Opana equivalent)
  • Metaxalone tablets (Skelaxin equivalent)
  • Methylphenidate hydrochloride tablets (Ritalin equivalent)

Location: Middlesex, NJ

26. Abiomed


“The only company in the world with exclusive labeling on ventricular assist devices for heart recovery”, Abiomed is on a mission to recover hearts and save lives. The company strives to develop innovative technologies to assist or replace the pumping function of a failing heart. With a comprehensive portfolio of products and services and the World’s Smallest Heart Pump, Abiomed is an emerging life sciences company in the northeast that is worth knowing.

Notable Products:

Location: Danvers, MA

27. ConforMIS


ConforMIS is a medical device company that advances patient care by “utilizing imaging technology to create personalized, patient-specific implants and instrumentation.” An industry leader in patient-specific technology, ConforMIS works to make knee implants fit the patients by combining advanced 3D imaging technology with innovative manufacturing capabilities. That’s more than enough to designate ConforMIS as an emerging life sciences company in the northeast.

Notable Products:

Location: Bedford, MA

28. Dynasplint Systems, Inc.

Dynasplint Systems, Inc.

Dynasplint is a medical device manufacturer specializing in reducing rehabilitation time and increasing range of motion. Dynasplint Systems feature spring-loaded tensioning devices that work like a physical therapist’s hands to stretch joints that lack range of motion. The company seeks to restore patients’ physical function and quality of life.

Notable Products:

Location: Severna Park, MD



“A full-service contract manufacturer of precision medical and surgical components, assemblies, complete devices, and finished class-critical implant devices,” MICRO delivers high quality products to the medical device industry. From research and development, to engineering and design, to prototyping and validation, to full-scale production, MICRO has an FDA-registered infrastructure and is cGMP-QSR compliant, making it an innovative life sciences company in the northeast.

Notable Products:

  • 5mm endoscopic dissector
  • 10mm babcock grasper
  • Insert molded trigger assemblies
  • Bladeless obturators for trocar ports

Location: Somerset, NJ

30. Excelsior Medical Corporation

Excelsior Medical

Excelsior Medical Corporation is a leading manufacturer of pre-filled saline and heparin flush syringes. The developer and manufacturer of SwabCap and SwabFlush, Excelsior also manufactures syringe pump and pharmacy dispensing pump systems. With its solutions for IV connector disinfection and its ability to deliver safer patient care, Excelsior is an innovative life sciences company in the northeast.

Notable Products:

Location: Neptune, NJ

31. US Endoscopy

US Endoscopy

US Endoscopy designs and supplies innovative diagnostic, therapeutic, and support accessories for the GI endoscopy and urology markets. With an eye to those devices that are urgently needed, US Endoscopy is committed to developing new products and solutions to improve patient care. Another reason that US Endoscopy is an innovative life sciences company in the northeast is that its people dedicates time and resources to non-profit, charitable, and environmental organizations and activities.

Notable Products:

Location: Mentor, OH

32. MicroGroup


MicroGroup supplies small-diameter tubing and solid stock and manufactures miniature metal components and assemblies for surgical instruments and medical implants. MicroGroup focuses on quality and medical field protocols to deliver components and assemblies for arthroscopy, biopsy/oncology, cardiovascular, cosmetic surgery, endoscopy, in vitro diagnostics, and more. MicroGroup’s speed, precision, and rapid prototyping center have led them to become an innovative life sciences company in the northeast.

Notable Products:

Location: Medway, MA

33. AtriCure, Inc.


AtriCure’s research and Afib clinical trials have resulted in ablation technology innovations for treating Afib, including AtriCure’s Isolator Synergy ablation system. A leader in atrial fibrillation solutions, AtriCure’s devices are groundbreaking and the company itself is an emerging life sciences company in the northeast that is worth knowing.

Notable Products:

Location: West Chester, OH

34. Unilife


Unilife designs, develops, manufactures, and supplies injectable drug delivery systems. With a broad portfolio of innovative platform-based technologies and a highly experienced team of industry leaders, Unilife seeks to improve patient care while protecting healthcare workers and reducing healthcare costs. Unilife has proven to be an innovative life sciences company in the northeast.

Notable Products:

Location: York, PA

35. Martech Medical Products

Martech Medical Products

Martech Medical Products grew from being a supplier of high quality extrusions and molded components to providing “concept to production services and support to the top medical device companies in the world.” Martech’s experienced engineers provide everything necessary for developing and producing medical devices of the highest quality, making it an innovative life sciences company in the northeast.

Notable Products:

  • Finished catheters
  • Machined devices
  • Valved products

Location: Harleysville, PA

36. Curbell Medical

Curbell Medical

Curbell Medical focuses on communication and strives to make hospitals more efficient and patients more content with its innovative healthcare integration solutions. Curbell has made the most of its partnerships to ensure innovation and seamless integration as it designs, develops, and manufactures a wide range of products. For drastically improving communications between nurses and patients and between technologies themselves, Curbell Medical has earned a name as an innovative northeastern life sciences company.

Notable Products:

Location: Orchard Park, NY

37. Physicians Interactive

Physicians Interactive

Physicians Interactive (PI) harnesses the power of worldwide healthcare professionals and life sciences company networks to “offer the life science industry a low-cost, virtual, multi-channel marketing approach that can be used to supplement currently promoted products, as well as non-promoted and orphaned products, that deliver benefits to physicians and patients.” PI seeks to be less disruptive to physicians’ daily workflow and utilizes behavior-based, integrated strategies to reach healthcare professionals when they make diagnosis, treatment, and prescribing decisions.

Notable Products:

Location: Reading, MA

38. Celldex Therapeutics

Celldex Therapeutics

At the core of Celldex Therapeutics is the belief that developing drugs for a number of devastating diseases rests on “harnessing the power of the immune system.” Celldex’s pipeline, therefore, is comprised of therapeutic antibodies, antibody drug conjugates, immune system modulators, and vaccines target to specific patient populations. The company’s commitment, growth, and promising pipeline have resulted in its becoming an innovative northeastern life sciences company.

Notable Products:


  • Hampton, NJ (corporate and research)
  • Branford, CT (clinical)
  • Fall River, MA (manufacturing)
  • Needham, MA (operations and research)

39. Forma Therapeutics

Forma Therapeutics

Forma Therapeutics, with two locations in the northeast, is committed to discovering and developing medicines to make a difference in cancer and other diseases driven by genetics. The company’s team of academic investigators, clinical experts, and corporate partners puts its deep biological and chemistry to use in rapidly creating high-quality, innovative drug candidates. Forma’s innovative drug discovery engine has given it a place as an emerging life sciences company in the northeast.

Notable Drug Discovery Platforms and Compound Archives:

  • Broadly diverse compounds
  • Diversity oriented synthesis (DOS) compounds
  • Shape-directed libraries


  • Watertown, MA
  • Branford, CT

40. Purdue Pharma

Purdue Pharma L.P.

A pharmaceutical company dedicated to improving patients’ lives, Purdue Pharma also dedicates itself to serving the healthcare community. Purdue is an innovative northeastern life sciences company with research, products, and medical programs centered on alleviating pain as well as addressing therapeutic needs related to sleep and gastrointestinal disorders.

Notable Products:

Location: Stamford, CT

41. Achillion


With a focus on bringing important new treatments to patients with HCV and immune disorders, Achillion is an innovative northeastern pharmaceutical company. The company’s expertise in biology and structure-guided design, along with a thorough understanding of patient and clinician needs, account for Achillion’s ability to advance a novel platform for the advancement of small molecule complement factor D inhibitors and other programs “discovered through Achilllion’s own proprietary internal drug discovery efforts.”

Notable Products:

Location: New Haven, CT

42. Rhodes Pharmaceuticals

Rhodes Pharmaceuticals

Rhode Pharmaceuticals is a specialty pharmaceutical company focused on controlled substances, technically challenging products, intellectual property, and vertical integration. Rhodes’ management team has extensive experience in the generic pharmaceutical industry, as well as manufacturing and distribution expertise. With a focus on developing high-opportunity products and intellectual property, Rhodes certainly is an emerging life science company in the northeast.

Notable Products:

  • Hydromorphone hydrochloride oral solution (authorized generic of Dilaudid)
  • Theophylline (Androus) extended-release tablets
  • Morphine sulfate extended-release tablets

Location: Coventry, RI

43. MultiCell Technologies

MultiCell Technologies

A clinical-stage biopharmaceutical company, MultiCell Technologies develops novel therapeutics and discovery tools to address treatment of neurological disorders, hepatic disease, and cancer. A key goal of the company is to develop a therapy for the control of cancer over a longer interval and of metastatic disease. As MultiCell Technologies owns exclusive rights to two U.S. patents and several other issued and pending patents regarding isolating and differentiating liver stem cells, it absolutely is an innovative northeastern life sciences company that you should get to know.

Notable Products:

Location: Woonsocket, RI

44. Denison Pharmaceuticals

Denison Pharmaceuticals

Providing analytical services, manufacturing and packaging, and a full turn-key solution, Denison Pharmaceuticals meets full cGMP compliance and offers only the highest quality in its manufacturing and packaging processes. With its efficient and personalized services, the company handles OTC, prescription, cosmetic, and veterinary products. Denison is making its mark as an emerging life sciences company in the northeast.

Notable Services:

Location: Lincoln, RI

45. BIND Therapeutics

BIND Therapeutics

BIND is a clinical-stage nanomedicine company that develops its novel targeted and programmable therapeutics, Accurins. Working primarily in oncology, BIND sees Accurins as the next stage in cancer therapy. BIND’s innovative strategies mark it as an emerging life sciences company in the northeast.

Notable Products:

Location: Cambridge, MA

46. Novavax


Novavax, Inc. is a clinical-stage biopharmaceutical company dedicated to creating next-generation vaccines to prevent serious infectious diseases like pandemic and seasonal flu and RSV. The company’s top science teams employ VLP technology and recombinant nanoparticle protein micelle technology to create vaccine candidates. Novavax is working to control the spread of these diseases with a single-use manufacturing system to enable mass production of recombinant protein nanoparticle vaccines in order to rapidly deliver customized vaccines during declared pandemics.

Notable Products:

Location: Gaithersburg, MD

47. Chromocell Corporation

Chromocell Corporation

A life sciences company seeking to improve consumer products and patient lives through groundbreaking science and technology, Chromocell focuses on discovering and developing flavors, nutritional ingredients, and therapeutics with its Chromovert technology. The company’s pioneering technology makes it possible to use “naturally occurring cells and receptors in high performance discovery platforms.” Chronicle’s work in therapeutics concentrates on analgesics and treating respiratory disorders and marks it as an emerging life sciences company in the northeast.

Notable Product: Chromovert Technology

Location: Brunswick, NJ

48. ProPharma Group


ProPharma Group provides qualification, compliance, and technical services to pharmaceutical, biotechnology, and medical device industries. With its leading industry knowledge, wealth of experience, and proven processes, ProPharma Group helps companies navigate the complicated landscape of the highly regulated life sciences environment and is an innovative northeastern life sciences company itself.

Notable Services:

Location: Newton, MA

49. Cherokee Pharma

Cherokee Pharma

With a team of experienced and dedicated scientists and a state-of-the-art cGMP facility with research and development capabilities, Cherokee Pharma is an emerging life sciences company in the northeast. The company is a “preeminent” provider of product development services for the pharmaceutical industry and specializes in drug delivery technologies for local and global pharmaceutical products.

Notable Services:

  • Development services
  • Project management
  • Development capabilities
  • Quality assurance

Location: Monmouth Junction, NJ

50. Sunovion


Sunovion considers patients’ and healthcare professionals’ needs when developing better treatments. Sunovion specializes in two areas of treatment: respiratory diseases and central nervous system disorders. With a targeted discovery and development program, Sunovion is working to improve people’s daily lives and is emerging as an innovative northeastern life sciences company.

Notable Products:

Location: Marlborough, MA

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